- Abemaciclib Intermediates
- I-Larotrectinib Intermediate
- Ivacaftor Intermediates
- I-AZD-9574 Intermediate
- I-AZD-5305 Intermediate
- I-Delafloxacin Intermediate
- I-Ponatinib Intermediates
- I-Baloxavir Intermediate
- I-Lisapram Intermediates
- I-Suzetrigine(VX548) Intermediate
- I-Resmetirol GL3196 Intermediate
- I-Dotinod Intermediates
- Abanye Abalamuli
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6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole CAS:1231930-33-8
ZhonghanUhlolojikelele Lomkhiqizo
I-6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[D]imidazole (i-CAS No. 1231930-33-8) iyindawo emaphakathi yemithi enomsebenzi wamakhemikhali aphezulu. Isakhiwo sayo esiyingqayizivele siqukethe amaqembu amaningi asebenzayo afana ne-bromine, i-fluorine, isopropyl ne-methyl. Lawa maqembu asebenzayo ayinikeza ikhono lokubamba iqhaza ekuphenduleni kwamakhemikhali okuhlukahlukene, okwenza kube impahla eluhlaza ebalulekile yokuhlanganiswa kwezidakamizwa ezihlukahlukene.
ZhonghanIfomula yesakhiwo
Ifomula yamangqamuzana | I-C11H12BrFN2 |
Isisindo samangqamuzana | 271.13 |
Inombolo ye-EINECS | 807-019-0 |
Iphuzu elibilayo | 353.4±22.0 °C(Kubikezelwe) |
Ukuminyana | 1.49 |
Izimo zokugcina | Kuvalwe endaweni eyomile, Ngezinga lokushisa Legumbi |
I-acidity coefficient (pKa) | 3.48±0.10(Okubikezelwe) |
Ikhodi Yamasiko | 2933998090 |
ZhonghanIzici ezingokomzimba
Lo mkhiqizo uvame ukuba khona ngendlela eqinile, futhi ukubukeka kwawo kungase kuhluke kuye ngenqwaba yokukhiqiza nobumsulwa. Ifomula yayo yamangqamuzana ithi C11H12BrFN2, futhi isisindo sayo samangqamuzana singama-271.13. Ngesikhathi sokugcinwa kanye nokuthuthwa, kufanele igcinwe yomile, ivalwe, futhi igweme ukushisa okuphezulu nokukhanya kwelanga okuqondile ukuze kuqinisekiswe ukuzinza kwayo kwamakhemikhali.
ZhonghanIzindawo Zokufaka Isicelo
I-6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[D]imidazole inohlu olubanzi lwezinhlelo zokusebenza ekuhlanganiseni kwemithi. Ingasetshenziswa njengendawo emaphakathi ezinyathelweni eziyisihluthulelo zokwenziwa kwezidakamizwa ezithile, ezibamba iqhaza ekuphenduleni kwamakhemikhali okuyinkimbinkimbi ukuze kukhiqizwe ama-molecule ezidakamizwa asebenza ngokwebhayoloji. Le mithi ingase isetshenziselwe ukwelapha izifo ezihlukahlukene, kuhlanganise nomdlavuza, izifo ezithathelwanayo, nezifo zemizwa.
Njengamanje, kunezinkampani eziningi ezisezingeni eliphakathi ezenza imithi emakethe ezikhiqiza futhi zithengise lo mkhiqizo. Lezi zinkampani zivame ukuba nolwazi olucebile lokukhiqiza kanye nemishini yokukhiqiza ethuthukisiwe, futhi zingahlinzeka amakhasimende ngemikhiqizo yekhwalithi ephezulu kanye nezinsizakalo ezinhle kakhulu. Lapho ekhetha umphakeli, amakhasimende ayalulekwa ukuthi anake izici ezinjengokuhlanzeka komkhiqizo, ukuzinza, ukupakisha nezindlela zokuthutha ukuze aqinisekise ulwazi lomkhiqizo owanelisayo.
Njengengxenye yemithi ebalulekile, i-6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[D]imidazole idlala indima engenakuthathelwa indawo emkhakheni wokuhlanganiswa kwemithi. Ngokuthuthuka okuqhubekayo kwemboni yezemithi, isidingo sayo semakethe sizoqhubeka sikhula, kulethe amathuba ebhizinisi ezinkampanini ezimaphakathi zokwenza imithi.