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Imikhiqizo Izigaba
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01
I-CAS1180132-17-5.jpg

5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine CAS:1180132-17-5

I-Pharmaceutical Intermediate 1180132-17-5, igama lekhemikhali 5-((4-ethylpiperazine-1-yl)methyl)pyridin-2-amine, iwukhiye osetshenziswayo onamathemba okusebenza abanzi emikhakheni yezokwelapha nemboni yamakhemikhali. Lokhu okuphakathi kwemithi kunokwakheka kwamakhemikhali okuyingqayizivele, ifomula yamangqamuzana C12H20N4, nesisindo samangqamuzana esingaba ngu-220.31. Inombolo yayo ye-CAS ithi 1180132-17-5, imvamisa isesimweni esiqinile esimhlophe noma esimhlophe, futhi ubumsulwa bomkhiqizo onikezwe inkampani yethu buphezulu obufinyelela ku-99%, okuqinisekisa ukusetshenziswa kwawo ngempumelelo ekuhlanganiseni kwemithi.

Njengempahla ebalulekile yokwenziwa kwemithi, i-1180132-17-5 idlala indima ebalulekile ekuhlanganisweni kwezidakamizwa ezilwa nomdlavuza njenge-Abemaciclib. I-Abemaciclib iyi-CDK4/6 inhibitor esebenza kahle kakhulu futhi isetshenziswa kabanzi ekwelapheni umdlavuza webele, ikakhulukazi ezigulini ezinomdlavuza webele we-hormone receptor-positive kanye ne-HER2-negative. Ngokulawula okunembile kwenqubo yokuhlanganisa, abaxhumanisi bethu bezemithi banikeza isiqiniseko sekhwalithi esizinzile nesithembekile sokukhiqizwa kwemithi efana ne-Abemaciclib.

    Xhumana nathi
    imininingwane yomkhiqizo

    Zhonghanincazelo yomkhiqizo

    Ngaphezu kwalokho, i-1180132-17-5 iphinde ibonise amandla okusetshenziswa okubanzi kwezinye izinkambu zemithi namakhemikhali. Izici zayo zamakhemikhali eziyingqayizivele kanye nokusebenza kabusha kwenza kube okubalulekile okuphakathi ekuhlanganiseni kwezinhlobonhlobo zezidakamizwa namakhemikhali. Ithimba lenkampani yethu le-R&D lihlala lihlola izindawo ezintsha zokufaka izicelo futhi lizibophezele ekuhlinzekeni amakhasimende ngemikhiqizo namasevisi ekhwalithi ephezulu kakhulu.

    Mayelana nokukhiqizwa nokulawulwa kwekhwalithi, inkampani yethu inemishini yokukhiqiza ethuthukisiwe kanye nesistimu yokuphatha ikhwalithi eqinile. Silandela izindinganiso zamazwe ngamazwe kanye nokucaciswa komkhakha ukuze siqinisekise ukuphepha nokwethembeka kwemikhiqizo yethu. Ngesikhathi esifanayo, siphinde sinikeze ngezinsizakalo zokukhiqiza ezenziwe ngokwezifiso futhi sinikeze ngemikhiqizo yokucaciswa okuhlukene nokupakishwa ngokuvumelana nezidingo zamakhasimende.

    Kafushane, i-pharmaceutical intermediate 1180132-17-5 ekhiqizwe yinkampani yethu inamathuba abanzi okusebenza kanye nenani lemakethe elibalulekile emikhakheni yezokwelapha nemboni yamakhemikhali. Sizoqhubeka nokusekela ifilosofi yebhizinisi lebhizinisi "yezinga eliphezulu, ezobuchwepheshe-okokuqala, isevisi ethembekile, ukwabelana nge-win-win", sinikeze amakhasimende imikhiqizo namasevisi angcono, futhi sikhuthaze ngokubambisana ukuthuthukiswa kwezimboni zemithi nezamakhemikhali.

    ZhonghanIfomula yesakhiwo

    Ifomula yamangqamuzana

    I-C12H20N4

    Isisindo samangqamuzana

    220.31

    Inombolo ye-EINECS

    806-688-6

    Izigaba ezihlobene

    API intermediates; uchungechunge lwasePomasini; Chemical Lesisemkhatsini

    Iphuzu elibilayo

    362℃

    Ukuminyana

    1.101

    Iphoyinti le-Flash

    173℃

    Isimo sesitoreji

    2-8°C(vikela ekukhanyeni)

    I-acidity coefficient (pKa)

    7.71±0.10

    Ikhodi Yamasiko

    2933599590

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